Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections
… Reports of waning vaccine-induced immunity against COVID-19
… (1) SARS-CoV-2-naïve individuals who received a two-dose regimen of the BioNTech/Pfizer
… (2) previously infected individuals who have not been vaccinated
… (3) previously infected and single dose vaccinated individuals
… SARS-CoV-2-naïve vaccinees had a 13.06-fold … increased risk for breakthrough infection with the Delta variant
… naïve vaccinees had a 5.96-fold … increased risk for breakthrough infection
… 7.13-fold … increased risk for symptomatic disease
… a greater risk for COVID-19-related-hospitalizations
… demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity
