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Intracellular reverse Transcription of Pfizer vaccine in vitro in human liver cell line

25 Febbraio 2022 by

… a recent study showed that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of human cells

… we investigated the effect … on the human liver cell line Huh7 in vitro

… Our results indicate a fast up-take of BNT162b2 into human liver cell line

… We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h

… In the BNT162b2 toxicity report, no genotoxicity nor carcinogenicity studies have been provided

… Further studies are needed to demonstrate the effect of BNT162b2 on genomic integrity

… including whole genome sequencing of cells exposed to BNT162b2

… as well as tissues from human subjects who received BNT162b2 vaccination

… The Pfizer EMA assessment report also showed that BNT162b2 distributes in the spleen

… adrenal glands … in the ovaries and testes

… no data on placental transfer of BNT162b2 is available from Pfizer EMA assessment report

… It is therefore important to investigate further the effect of BNT162b2 on other cell types and tissues both in vitro and in vivo

Peter McCullough